Clinical research progress of deep brain stimulation for Meige's syndrome

Abstract

Meige's syndrome (MS) is a segmental dystonia characterized by blepharospasm and oromandibular dystonia. Early treatment with medication or local injection of botulinum toxin can achieve certain therapeutic effects, but long ‐ term use leads to decreased efficacy and adverse reactions, posing challenges to the treatment of the disease. Deep brain stimulation (DBS) has become a new treatment method for Meige's syndrome due to its safety, effectiveness, minimally invasive nature, reversibility, and controllability. This article reviews the clinical manifestations, pathogenesis of Meige's syndrome, as well as the mechanism and efficacy of DBS treatment, to improve clinical understanding of DBS treatment for Meige's syndrome.

DOI: 10.3969/j.issn.1672⁃6731.2024.07.003