Research progress on cerebrospinal fluid markers in traumatic brain injury

Abstract

The pathophysiological mechanism of traumatic brain injury (TBI) is complex, and the changes of cerebrospinal fluid markers can reflect the changes of brain microenvironment and neurometabolic processes, and are not easily interfered by peripheral factors. Compared with blood markers, they are more stable and reliable. This article reviews the research progress of main cerebrospinal fluid markers in TBI, in order to improve the understanding of the pathogenesis of TBI and achieve precise treatment of TBI.

DOI: 10.3969/j.issn.1672⁃6731.2023.10.003