Progress of fMRI on the recurrence and pseudoprogression in glioblastoma

Abstract

The treatment and prognosis of recurrence and pseudoprogression of glioblastoma are completely different. Therefore, distinguishing the two has become a clinical focus. However, both can be manifested as new or increasing enhancing lesions with peripheral edema on conventional MRI, and their clinical manifestations lack specificity, such as increased intracranial pressure (ICP), local neurological deficits and so on. Therefore, it is impossible to distinguish the two from clinical and conventional MRI. In recent years, with the increasing development of imaging technology, a variety of functional imaging technologies have shown great potential to distinguish the two. This article summarized the application progress of functional imaging technologies on differential diagnosis of recurrence and pseudoprogression in glioblastoma.

doi：10.3969/j.issn.1672⁃6731.2022.04.015