Research progress of essential tremor⁃Parkinson's disease

Abstract

Essential tremor (ET) and Parkinson's disease (PD) are two common movement disorders. A large number of clinical evidence found that a part of patients with early diagnosis of ET could evolve into PD. These patients are diagnosed with essential tremor⁃Parkinson's disease (ET⁃PD). However, there is a lack of diagnostic criteria for ET⁃PD, and the overlap of clinical symptoms of ET and PD makes the identification of ET⁃PD challenging. Here, with an aim to improve the levels of clinical diagnosis and treatment, we summarize the research progress of ET⁃PD in epidemiology, clinical characteristics, pathology and pathophysiology, electrophysiological characteristics, neuroimaging characteristics, genetics and treatment in order to improve the level of clinical diagnosis and treatment.

doi：10.3969/j.issn.1672⁃6731.2022.04.004