Analysis of related risk factors of acute ischemic stroke after surgical clipping of ruptured intracranial aneurysms

Abstract

Objective To analyze risk factors related to acute ischemic stroke after intracranial aneurysm clipping. Methods From January 2013 to January 2018, 267 cases of intracranial ruptured aneurysm in our hospital were collected retrospectively. All patients were given intracranial aneurysm clipping, ventricular drainage and decompression with bone flap vemova. Univariate and multivariate backward Logistic regression analysis were used to analyze the risk factors for ischemic stroke after intracranial aneurysm clipping. Results There were 62 patients (23.22%) with acute ischemic stroke after intracranial aneurysm clipping. Logistic regression analysis showed that hypertension (OR=1.695,95%CI: 1.247-2.631; P=0.006), bloodglucose (OR=4.206,95%CI:2.771-6.284; P=0.000), Hunt⁃Hessgrade ≥ Ⅲ (OR=1.443,95%CI:1.205-1.872; P=0.017),ventricular hemorrhage (OR=1.947,95%CI:1.465-2.973; P=0.001)and acute hydrocephalus (OR=3.221,95%CI:2.218-4.960; P=0.000) were risk factors for acute ischemic stroke after intracranial aneurysm clipping. Conclusions The hypertension, blood glucose increased on admission, preoperative Hunt ⁃ Hess grade ≥ Ⅲ, ventricular hemorrhage and acute hydrocephalus were risk factors for acute ischemic stroke after clipping of intracranial aneurysm rupture.

DOI：10.3969/j.issn.1672⁃6731.2020.09.012