Genetic diagnosis and treatment progress of primary periodic paralysis

Abstract

Primary periodic paralysis is autosomal dominant genetic skeletal muscle ion channelopathy. It is characterized by episodes of muscle weakness associated with lower, normal or elevated serum potassium. The genetic diagnosis process of periodic paralysis is proposed based on the latest research progress and clinical classifications. Advances in therapy also are reviewed in this study.

doi: 10.3969/j.issn.1672-6731.2014.06.003