Clinical observation of early enteral nutrition therapy for patients with severe traumatic brain injury

Abstract

This paper aims to compare the effect on early prognosis of post-traumatic early enteral nutrition therapy and central venous catheterization parenteral nutrition therapy in patients with severe traumatic brain injury (sTBI). The results showed that on 7 and 14 d, serum total protein [(62.04 ± 2.09) and 66.04 ± 2.27) g/L], albumin [(37.75 ± 2.86) and (43.43 ± 2.37) g/L] and prealbumin [(177.87 ± 13.89) and (199.43 ± 11.01) mg/L] in patients treated with early enteral nutrition were all higher than patients treated with parenteral nutrition (P = 0.000, for all). On 7 d the stomach bleeding rate of patients treated with enteral nutrition (14.29%, 4/28) was lower than patients treated with parenteral nutrition (39.29%, 11/28), and the difference was statistically significant (χ² = 4.462, P = 0.035). On 14 d, no one case of stomach bleeding occured in patients with enteral therapy, while 4 cases of stomach bleeding (14.29%) occured in patients with parenteral therapy, and the difference was not significant ( χ² = 2.423, P = 0.120). The difference of lung infection rate between different treated patients was not statistically significant ( χ² = 0.287, P = 0.592). Early enteral nutrition therapy for severe traumatic brain injury patients can provide adequate nutritional support and reduce the incidence of stomach bleeding.

doi: 10.3969/j.issn.1672-6731.2014.04.016