Parasomnias in Parkinson's disease

Abstract

Sleep disorders, as one of the most common non-motor manifestations of Parkinson's disease (PD), have caused serious impact on the quality of life in PD patients. Parasomnias as an important part of sleep disorders associated with PD, have become hot topics in recent years. Parasomnias include rapid eye movement sleep behavior disorder (RBD), sleep-related movement disorders and wakefulness disturbance, while wakefulness disturbance consists of excessive daytime sleepiness (EDS) and sleep attacks. Some of these disorders, including RBD and EDS may occur before the motor symptoms of PD and become potential early markers of the disease. Sleep-related movement disorders include restless legs syndrome (RLS) and periodic limb movement (PLM). In addition, a part of them such as EDS is related to pharmacologic treatment. So get a better knowledge of sleep disorders in PD, will not only help to improve the quality of life in PD through timely intervention, but make it possible to identify people at risk in developing PD and carry out neuroprotective therapy as early as possible.