Progress on neuromodulation for treatment of mental disorders

Abstract

Traditional treatment methods for mental disorders include pharmacotherapy and psychotherapy. However, some patients are unable to effectively control their symptoms. Neuromodulation technique, which can be implemented through invasive or non⁃invasive approaches, have shown promise in improving the psychiatric symptoms of individuals with mental illnesses by intervening in neural circuits. This paper summarizes the current applications of neuromodulation technique for various mental disorders, including obsessive⁃compulsive disorder, depression, Tourette's syndrome, bipolar affective disorder, autism spectrum disorder, substance dependence and schizophrenia. Additionally, it analyzes the prospects and challenges of neuromodulation technique in the treatment of mental disorders, with the aim of guiding future neuromodulation therapy for mental disorders.

doi：10.3969/j.issn.1672⁃6731.2025.01.008