Multicenter study on prognostic influencing factors of endovascular treatment for acute basilar artery occlusion

Abstract

Objective To screen the prognostic influencing factors of patients with endovasculartreatment for acute basilar artery occlusion (ABAO⁃EVT). Methods The baseline, clinical and follow⁃updata of 215 patients with ABAO⁃EVT from October 2017 to August 2022 in The First Affiliated Hospital ofUniversity of Science and Technology of China, Linyi People's Hospital of Shandong and Maoming People'sHospital of Guangdong were retrospectively collected, including sex, age, stroke or transient ischemic attack(TIA), hypertension, diabetes, coronary heart disease, atrial fibrillation, smoking and drinking history,National Institutes of Health Stroke Scale (NIHSS) score, intravenous thrombolysis, first pass effect, times ofembolectomy, extended Thrombolysis in Cerebral Infarction (eTICI), and modified Rankin Scale (mRS) score90 d after operation. According to the 90 d mRS score, the patients were divided into 2 groups: goodprognosis group (mRS score 0-3, n = 93) and poor prognosis group (mRS score 4-6, n = 122). Univariateand multivariate stepwise Logistic regression analyses were used to screen the neurological prognosticinfluencing factors of ABAO ⁃ EVT patients 90 d after operation. Results Logistic regression analysisshowed that the baseline NIHSS score increased was a risk factor for poor prognosis of ABAO⁃EVT patients(aOR = 0.936, 95%CI: 0.907-0.965, P = 0.000; aOR = 0.940, 95%CI: 0.910-0.970, P = 0.000), with the firstpass effect (aOR = 5.752, 95%CI: 2.875-11.508; P = 0.000), eTICI grade 2c-3 (aOR = 7.113, 95%CI: 3.665-13.805; P = 0.000) were protective factors for good prognosis. Conclusions Low baseline NIHSS score,first pass effect and reperfusion level of eTICI 2c-3 are all protective factors for good neurological prognosisof ABAO⁃EVT patients.

doi：10.3969/j.issn.1672⁃6731.2024.11.008