The past, present and future of drug therapy for epilepsy

Xiang⁃song SHI, Su⁃meng SONG, Jian⁃yang XU

Abstract


Epilepsy is a common clinical neurological disease, the pathogenesis of which has not yet been elucidated. As the main treatment, antiepileptic seizure medicine (ASM) fights against seizures rather than improve epilepsy. According to the chronological order of "past", "present" and "future", this article reviews the development history of ASM from the aspects of pharmacokinetics, pharmacological mechanism, indications, efficacy and adverse reactions, and looks forward to the future development direction. It can provide a theoretical basis for the prevention and treatment of epilepsy.

 

doi：10.3969/j.issn.1672⁃6731.2023.02.002


Keywords


Epilepsy; Anticonvulsants; History of medicine; Review

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