Neuromyelitis optica spectrum disorders and pregnancy

Qiang LIU, Qing ZHANG, Chao QUAN

Abstract


Neuromyelitis optica spectrum diseases (NMOSDs) is an autoimmune disease of central nervous system, which occurs frequently in women of childbearing age. NMOSDs may affect pregnancy planning and fertility, and the effect on pregnancy outcome is not clear. Pregnancy can cause changes in the immune system and sex hormone levels, which results in NMOSDs recurrence and progression. Reasonable immunosuppressive treatment may effectively avoid pregnancy⁃related disease activities using low⁃dose corticosteroids, azathioprine and rituximab may be safe during pregnancy and after delivery.

 

doi：10.3969/j.issn.1672⁃6731.2022.01.005


Keywords


Neuromyelitis optica; Pregnancy; Femininity; Review

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