Introduction of newly identified tumor types in the 2021 WHO Classification of Tumors of the Central Nervous System (fifth edition)

Zhi LI

Abstract


The 2021 WHO Classification of Tumors of the Central Nervous System (fifth edition) focused on promoting the molecular pathological diagnosis in the role of the central nervous system tumor classification. According to the tumor histopathological morphology and genetic features, the new edition tumors classification added 22 tumor types or subtypes, which reflects the latest recognition of tumor clinical pathology and molecular genetics. In this paper, we will briefly introduce the new tumors with specific histopathological features in new edition tumors classification, with the purpose of understanding the biological behavior of these tumors and improving the accuracy of diagnosis, so as to benefit patients.

 

doi:10.3969/j.issn.1672⁃6731.2021.09.007


Keywords


Central nervous system neoplasms; Guidelines; World Health Organization; Neuropathology; Pathology, molecular; Review

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