Interpretation on the diagnostic molecular parameters in the 2021 WHO Classification of Tumors of the Central Nervous System (fifth edition)

Abstract

The 2021 WHO Classification of Tumors of the Central Nervous System (fifth edition) introduces a series of molecular biomarkers and new types/subtypes, which highlight the importance of integrated diagnoses and layered reports. The new edition tumors classification is reflections of the understanding in this field at present. Herein, we review the key molecular diagnostics and detection techniques, aiming to facilitate better understanding and more appropriate management for the tumors of the central nervous system.

doi：10.3969/j.issn.1672⁃6731.2021.09.005