Diagnosis and treatment of pineal region tumors

Abstract

Indiscriminate neuroendoscopic biopsy of pineal region tumors is not advisable. For germ cell tumors with elevatedtumor markers ( β ⁃ human chorionic gonadotropin and alpha ⁃ fetoprotein), biopsy is not necessary, and neoadjuvant chemotherapy can be used for stratified management. If diagnosis of germ cell tumors is clinically highly suggestive, neuroendoscopic biopsy or diagnostic chemotherapy may be recommended. Except for those two types of the pineal tumors, others can be removed by craniotomy, followed by radiotherapy and chemotherapy according to the pathological results or only followed up.DOI：10.3969/j.issn.1672⁃6731.2020.04.002