Optimization of scan time for resting ⁃state fMRI in clinical application

Abstract

Objective To study the optimization of scan time for resting⁃state functional magnetic resonance imaging (fMRI) in clinical application. Methods Fractional amplitude of low ⁃ frequency fluctuation (fALFF) was performed to analyse the resting ⁃ state fMRI data of 6 and 12 min scan time, respectively. The resting⁃state fMRI data of 16 subacute pontine infarction patients and 16 normal controls were analysed. The activations of default mode network (DMN) were compared between the resting⁃state fMRI data of 6 and 12 min scan time. Results The activations of DMN were both found in patient and normal groups. There was no significant difference between the resting⁃state fMRI data of 6 and 12 min scan time (P > 0.05). Conclusion The optimization of scan time for resting⁃state fMRI was 6 min and it is very important for clinical application.

DOI：10.3969/j.issn.1672-6731.2011.03.009