Endoscopic transnasal surgery for treatment of cerebrospinal fluid rhinorrhea

Abstract

Objective To explore the feasibility and curative effect of endoscopic transnasal surgery in the treatment of cerebrospinal fluid (CSF) rhinorrhea. Methods and Results From November 2011 to June 2018, a total of 198 patients with CSF rhinorrhea underwent endoscopic transnasal surgery in our hospital. There were 191 cases being repaired successfully in the first surgery, and the success rate of primary repair was 96.46% (191/198). Postoperative rhinorrhea recurred in 7 cases (3.54%, 7/198), and they were repaired successfully in the second surgery. After operation, 14 cases (7.07% ) suffered from intracranial infection, and were cured by antibiotic therapy. One case (0.51%) with deep venous thrombosis of right lower limb and 2 cases (1.01%) with intermuscular venous thrombosis of lower limbs were treated by low molecular heparin anticoagulant therapy. One case (0.51% ) died of septic shock. All survival patients were followed up for (36.27 ± 15.36) months, and none of them relapsed. Conclusions Endoscopic transnasal surgery has a high success rate and less trauma in the repair of CSF rhinorrhea. Postoperative intracranial infection should be prevented as the main postoperative complication.

DOI: 10.3969/j.issn.1672-6731.2019.04.006