Research progress of spinal muscular atrophy treatment in children

Abstract

Spinal muscular atrophy (SMA) is the most common fatal neurogenetic disease in infant period. Clinical manifestations of SMA include symmetrical and progressive weakness and atrophy of proximal limbs. Based on age of incidence, it is divided into child-onset SMA and adult-onset SMA. Child-onset SMA has the highest incidence rate. This article summarizes the research progress of SMA therapy in recent years to provide new thoughts for the treatment of SMA.

DOI: 10.3969/j.issn.1672-6731.2018.04.010