Research progress of idiopathic inflammatory demyelinating diseases

Abstract

Idiopathic inflammatory demyelinating diseases (IIDDs) belongs to autoimmune diseases of nervous system, which is a group of spectrum disorders including multiple sclerosis (MS), neuromyelitis optica spectrum disorders (NMOSDs), acute disseminated encephalomyelitis (ADEM) and other related diseases. It often occurs in young adults, and the course is relapse-remitting, often leaving neurological sequelae in each episode, and ultimately leading to nerve dysfunction. Early diagnosis, close disease monitoring and prompt treatment are the keys to improve the long-term prognosis of patients. During the period of Twelfth Five-Year Plan for National Economic and Social Development, our team devoted ourselves to the studies of IIDDs and achieved results in the etiology, pathogenesis, clinical features, diagnosis and differential diagnosis, and treatment strategies of the disease respectively. In this paper, we briefly review the above research findings.

DOI: 10.3969/j.issn.1672-6731.2018.02.005