Clinical study on transsphenoidal approach under endoscope for repairing cerebrospinal fluid rhinorrhea after pituitary adenoma resection

Abstract

Objective To summarize the experience of endoscopic surgery by transsphenoidal approach for repairing cerebrospinal fluid (CSF) rhinorrhea after pituitary adenoma resection.  Methods Clinical data, operation skills and follow-up data of 16 cases of persistent CSF rhinorrhea after pituitary adenoma resection from March 2009 to July 2014 were retrospectively analyzed.  Results All patients were repaired by endoscopic transsphenoidal approach, 13 cases (13/16) were successful by one reparative surgery, 2 cases (2/16) were successful by the second repairment, and one case (1/16) was failed by several endoscopic surgeries, but was successfully repaired by craniotomy. One case presented intracranial infection after surgery, and recovered after taking ceftriaxone. After postoperative follow-up for 6 months to 2 years (average 12 months), no tumor recurrence or CSF rhinorrhea recurrence occurred.  Conclusions Endoscopic transsphenoidal approach for repairing CSF rhinorrhea after pituitary adenoma resection was safe and effective. It can be widely used in clinic.

DOI: 10.3969/j.issn.1672-6731.2017.06.012