Mild cognitive impairment in Parkinson's disease

Abstract

Cognitive dysfunction is common non-motor symptom (NMS) in Parkinson's disease (PD), which affects the patients' quality of life and increases the burden of caregivers. Cognitive dysfunction in PD can be mild cognitive impairment (MCI) or dementia. MCI presents in the early stage of PD and the incidence rate is increasing with the disease progression. In some cases it can advance to dementia. The diagnosis of MCI in PD includes inclusion criteria, exclusion criteria and damage level evaluation. Non-pharmacological therapy, such as exercise and cognitive behavior therapy (CBT) can improve the symptoms of MCI in PD, while the pharmacological treatment remains to be further studied.

DOI: 10.3969/j.issn.1672-6731.2016.06.002