A classic drug phenobarbital and its application progress in treating epilepsy

Abstract

As a classic antiepileptic drug (AED), phenobarbital has been used in clinic for more than 100 years and is available in the majority of countries in the world. Accepted as the drug of choice for controlling seizures in developing countries by World Health Organization (WHO), phenobarbital can effectively lessen the treatment gap. In this paper, the utilization of phenobarbital around the world, and its curative effect and adverse drug reaction were reviewed.

DOI: 10.3969/j.issn.1672-6731.2016.01.009