Amyloid β-related central nervous system vasculitis

Zhuo LI, Yue-shan PIAO, De-hong LU

Abstract


Amyloid β (Aβ)-related central nervous system (CNS) vasculitis, which is also known as cerebral amyloid angiopathy (CAA)-related CNS vasculitis, is characterized by the presence of chronic inflammation within or around the walls of Aβ-deposit blood vessels. Cerebral biopsy is the gold standard for diagnosis of A β-related CNS vasculitis considering the atypical clinical features, cerebrospinal fluid (CSF) and neuroimaging findings of some patients. This paper reviewed the pathogenesis, neuropathology, clinical features, treatment and prognosis of Aβ-related CNS vasculitis.

 

DOI: 10.3969/j.issn.1672-6731.2016.01.002


Keywords


Amyloid beta-protein; Vasculitis, central nervous system; Pathology; Review

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