Outcome after hemispherectomy in patients with drug-resistant epilepsy

Abstract

Hemispherectomy, as well as hemispherotomy, is an effective treatment for children and adolescents with drug-resistant epilepsy. The procedure is considered in children and adolescents with hemispheric damage due to congenital (e.g. malformation of cortical development), acquired (e.g. perinatal cerebral infarction) or progressive diseases (e.g. Rasmussen encephalitis). As the main objective of this procedure, seizure control can be achieved in up to 80% of selected cases. Besides, the cognitive and motor function as well as the quality of life has shown good outcome.

DOI: 10.3969/j.issn.1672-6731.2015.11.016