Curative effect of monosialotetrahexosylganglioside combined with Xingnaojing injection on acute cerebral hemorrhage

Abstract

This paper aims to observe the curative effect of monosialotetrahexosylganglioside combined with Xingnaojing injection on acute cerebral hemorrhage. A total of 120 cases with acute cerebral hemorrhage were treated with Xingnaojing injection monotherapy (control group, N = 60) or monosialotetrahexosylganglioside combined with Xingnaojing injection (combined treatment group, N = 60). Bleeding amount and National Institutes of Health Stroke Scale (NIHSS) scores of 2 groups were both significantly reduced on the 21th day after treatment (P = 0.000, for all), but bleeding amount and NIHSS scores in combined treatment group were significantly lower than those in control group (P = 0.000, for all). After 21 d treatment, total effective rate of combined treatment group was 86.67% (52/60), which was significantly higher than that of control group [66.67% (40/60); χ² = 1.493, P = 0.024]. For patients with acute cerebral hemorrhage, monosialotetrahexosylganglioside combined with Xingnaojing injection can significantly improve the neurological function.

DOI: 10.3969/j.issn.1672-6731.2015.07.014