A cross-sectional study of affective, psychiatric, cognitive disorders and motor complications of Parkinson's disease

Abstract

Objective  To investigate the prevalence, diagnosis and treatment of depression, anxiety, psychiatric symptom, cognitive impairment and motor complications of Parkinson's disease (PD).  Methods  Face to face interview was carried out among patients with idiopathic PD from Outpatient Department of Neurology, Ruijin Hospital affiliated to Shanghai Jiaotong University School of Medicine from March to May 2015. Self-Rating Depression Scale (SDS), Self-Rating Anxiety Scale (SAS), Mini-Mental State Examination (MMSE) were used for evaluation of depression, anxiety and cognitive impairment.  Results  A total of 55 patients with PD were enrolled in this study. Prevalences of depression, anxiety, psychiatric symptom and cognitive impairment of PD were 16.36% (9/55), 14.55% (8/55), 23.64% (13/55) and 9.09% (5/55), respectively. Ratio of previous diagnosis and treatment were 2/9, 2/8, 2/13 and 1/5, respectively. Prevalences of fluctuation and dyskinesia were 27.27% (15/55) and 9.09% (5/55), separately. There were no significant differences in prevalences of depression (P = 0.858), anxiety (P = 0.188), psychiatric symptom (P = 0.926), cognitive impairment (P = 0.286), fluctuation (P = 0.205) or dyskinesia (P = 0.417) between male and female PD patients.  Conclusions  Prevalences of depression, anxiety, psychiatric symptom, cognitive impairment and motor complications of PD were high, while ratios of diagnosis and treatment were relatively low.

DOI: 10.3969/j.issn.1672-6731.2015.06.010