Significance of adipose tissue-derived stem cells regulate CD4+ T cell immune in the treatment of multiple sclerosis
Abstract
Adipose tissue-derived stem cells (ADSCs) are genetically engineered seed cells with immunomodulatory effects, widely used in the treatment of autoimmune diseases. This article focuses on the immunomodulatory effects of adipose tissue-derived stem cells on CD4+ T cell subsets, including T helper cell (Th) 1, 2, 17 and regulatory T cell (Treg), and its clinical significance in the treatment of multiple sclerosis.
doi: 10.3969/j.issn.1672-6731.2014.10.005
Keywords
Mesenchymal stem cells; Adipocytes; T-lymphocytes; Multiple sclerosis; Encephalomyelitis, autoimmune, experimental; Review
This work is licensed under a Creative Commons Attribution 3.0 License.